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doi: 10.1016/j.fbr.2020.10.003 433 VianaR.CarreiroT.CouceiroD.DiasO.RochaI.TeixeiraM

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A great example is the ECLIPSE study (Evaluation of COPD Longitudinally to Identify Predictive Surrogate Endpoints) which is a large observational study of COPD patients and controls conducted at 46 centers in 12 countries aimed at defining COPD phenotypes and identifying biomarkers and genetic parameters that help to predict disease progression

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