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Additionally, the peptide inhibits acetyl-CoA carboxylase activity in hepatocytes and adipocytes, the rate-limiting enzyme in fatty acid synthesis

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Emerging therapeutic research positions resveratrol as a dual modulator capable of normalizing this leptin-APN axis imbalance, suggesting its lipid-modulating efficacy in PCOS arises through pleiotropic mechanisms involving adipokines pathways related to leptin and APN (80)

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