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Nicotinamide N-methyltransferase as a potential therapeutic target in neurodegenerative diseases

NNMT Research Relevance: Used in controlled enzyme and pathway investigations

Fluorescence was measured at 4, 24, 48 and 72 h after treatment at 485 nm excitation and 530 nm emission on a SpectraMax M3 microplate reader (Molecular Devices)

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But some patients absorb less than expected and need additional sublingual or IM B12

When pernicious anaemia is suspected, testing for anti-intrinsic factor antibodies (and sometimes anti-parietal cell antibodies) is recommended