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doi: 10.1001/jama.289.2.179 138 ThompsonW

Global liver disease burdens and research trends: analysis from a Chinese perspective

Notably, azithromycin, more commonly prescribed than others, appears to cause chronic DILI in over 20% of cases, particularly in patients with underlying liver disease [121]

[DOI] [PubMed] [Google Scholar] Poli G, Albano E, et al

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Similarly, in high-fat dietinduced (HFD induced) pre-diabetic rats subjected to cardiac ischemiareperfusion injury, administration of the mitochondrial fusion promoter M1 (2 mg/kg), either alone or in combination with the Drp1 inhibitor Mdivi-1 (1.2 mg/kg), significantly reduced mitochondrial dynamics imbalance, ROS generation, swelling, and membrane depolarization, which collectively decreased infarct size and arrhythmias while improving left ventricular function [177]