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Experimental validation Unfortunately, among the list of different proteins identified as putative targets in Table 1, only AChE and NLGN4X were commercially available as recombinant human proteins with a degree of purity and in the appropriate soluble form suitable to perform the experiments

placebo group n = 12, 10 males and 2 females), in a double blind, placebo controlled crossover design

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Hypoxia and the stabilization of HIF-1 can directly enhance this pathway through distinct molecular mechanisms

a , Immunoblot analysis of HEK293T cells overexpressing GAPDH or Hs PEX39 (1/300 dilution of cellular lysate)

It has a detoxifying effect