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Although L-carnitine deficiency is an infrequent problem in a healthy, well-nourished population consuming adequate protein, many individuals within the population appear to be somewhere along a continuum, characterized by mild deficiency at one extreme, and tissue pathology at the other
See, also, this June 2022 article warning that "life-threatening spikes of digoxinemia could occur, especially after 1-year treatment [for AF] with digoxin." See, also, this August 2022 case report of a dog diagnosed with heart failure and AF and treated with digoxin developed digitalis toxicity and showed a high concentration of plasma digoxin, with these symptoms disappearing 5 days after withdrawal of the digoxin medication
Trimethylamine-N-oxide: A novel biomarker for the identification of inflammatory bowel disease