heteroplasmy and glutathione Nuclear genetic control of mtDNA copy number in humans MtDNA heteroplasmy controls tumor immune

MtDNA heteroplasmy controls tumor immune reprogramming through mitochondrial translation bioRxiv Mitochondrial DNA has always been the odd relative in genetics: tiny, separate from the main genome, and packed inside the cell's energy factories. Unlike nuclear DNA, mtDNA exists in many copies per Mitochondrial DNA: a molecular switch driving sterile neuroinflammation Translational Neurodegeneration Springer Nature Link Progressive increase in mtDNA 3243A>G heteroplasmy causes abrupt transcriptional reprogramming PNAS Evidence based pathogenesis and treatment of ulcerative colitis: A causal role for colonic epithelial hydrogen peroxide Complex II Bioblast

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