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Turk Thorac

Introduction Autism spectrum disorder (ASD) is a pervasive neurodevelopmental disorder characterized by impaired communication and social interaction, as well as repetitive/stereotyped behaviors ( Admittedly, numerous publications have indicated that the pathogenesis of ASD was affected by immune dysregulation/inflammation, oxidative stress, and mitochondrial dysfunction ( Strikingly, existing evidence has indicated that Nrf2 plays an important role in immune dysregulation/inflammation, oxidative stress, and mitochondrial dysfunction

Gerhardt S, Mohajeri MH

doi: 10.1073/pnas.0509531103

While former studies suggested that regressive forms of onset were not common in ASD, more recent investigations indicate that the rates are quite high and may be under-reported

Glutathione neutralizes them by donating an electron, stabilizing the free radical without becoming unstable itself