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The list includes cytochrome c oxidase (the terminal electron-transport-chain enzyme), Cu/Zn superoxide dismutase (an antioxidant enzyme), lysyl oxidase (which cross-links collagen and elastin in extracellular matrix), tyrosinase (in melanin synthesis), dopamine beta-hydroxylase (in neurotransmitter synthesis), and others

ITC characterizes the thermodynamic properties of a ligand binding reaction, and thus allows a quantitative measurement of both binding affinity and stoichiometry

Glutathione is a powerful antioxidant naturally produced in the body, made up of three amino acids: cysteine, glutamine, and glycine

CD44 is a key factor in the regulation of BBB function

Raper SE, Wilson JM, Yudkoff M, Robinson MB, Ye X, Batshaw ML

The studys novelty lies in its systematic, integrative approach to assessing diverse sweeteners under consistent conditions, with an emphasis on neurochemical and redox biomarkers