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Glutathione protects mice from lethal sepsis by limiting inflammation and potentiating host defense

Based on this mechanism, Sotorasib and Adagrasib achieved meaningful clinical activity in patients with KRAS G12C-mutant non-small cell lung cancer, marking the beginning of the era of direct KRAS inhibition [1][2]

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In fact, it has been able to counter the effects that NSAIDs have on the gut lining so well that it has been nicknamed by many medical researchers as the antidote to NSAIDs

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