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However, ALC administration could show neuropathy improvement in patients with non-cancer conditions such as diabetes[]

This approval was based on the SELECT trial, which demonstrated a 20% reduction in cardiovascular events

Morovic P, Gonzalez Moreno M, Trampuz A, Karbysheva S

Rather, reconciliation updates the prior rebate amount owed to CMS, if any, by a manufacturer of a Part D rebatable drug so that the rebate amount ultimately reflects a more precise calculation of the rebate amount, as required by section 1860D-14B(a)(1) of the Act, to account for shifts in the underlying data following additional time for claims run-out after the Rebate Report is issued as well as subsequently identified data integrity issues