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Inflammatory cytokines induce protein tyrosine nitration in rat astrocytes

Hence folic acid lack inhibits secretion too (6)

However, the different kinetics of their induction and the distinct consequences of inhibition of the endogenous miRNAs suggest that miR-4488 may tame the proinflammatory response already at low levels of stress, whereas miR-4734 restricts the proinflammatory response only at a higher threshold

Moreover, the response is age-dependent, with young adults demonstrating more consistent and robust improvements compared to older adults

doi:10.1021/acs.jmedchem.8b01153 3