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Description

Itaconate is synthesized from cis-aconitate in the TCA cycle by IRG1 in macrophages after LPS stimulation (132)

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But it must be in limited quantities

Genetics and Transcription The coding region of the human SOD1 gene (9307bp, 21q22.11, Entrez Gene ID 6647) consists of five exons interrupted by four introns (Figure 1), which together code for the monomeric SOD1 polypeptide