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in 2019

Case 6 , 8792 (2022)

The Zr released from Mn-MOF downregulated GSH efficiently (Figure 5G), thus elevating Mn-MOF-induced ROS concentration, leading to the deactivation of GPX4 and ROS-enhanced ferroptosis

Targeting the entire system rather than focusing on a single element is considered the optimal approach to interfere with ageing and mitigate neurodegeneration