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Homocysteine thiolactone: metabolic origin and protein homocysteinylation in humans

ROS-responsive carriers) that release inhibitors precisely during oxidative bursts, ensuring ferroptosis is counteracted at the most critical moments

HW, SH, XF, WC and JX revised the manuscript

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Additionally, in IPF lungs, mesenchymal progenitor cells (MPCs) display cancer-like features driven by a CD44/Brg1/PRMT5 axis, which epigenetically silences tumor suppressors RBL1 and PTEN, supporting self-renewal and fibrogenesis [93]

To further verify that this phospho-specific binding recognises the S309 residue, we repeated the assay in HT-29 cells reconstituted with either WT or S309A-mutant RIPK1