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Diagnosis needs to be combined with patient history, symptom assessment (Ocular Surface Disease Index), and auxiliary examination [tear film stability: break-up time (BUT) test and tear secretion: Schirmers test] (Schiffman et al., 2000

In the US, the neuromodulators we use include Botox, Dysport, Xeomin, Jeuveau, and Daxxify

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For patients with a history of alcohol abuse or excess and evidence of liver disease, further laboratory tests should be done to exclude other etiologies and to confirm the diagnosis (Class I, level C)