glutathione causes kidney failure Chronic Disease: Stages, Treatments & Nutrition Hacks NRF2 in kidney physiology and

doi: 10.1038/s42255-023-00756-4 92 AngelovaPREsterasNAbramovAY

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Previous studies in keratinocytes indicated that adequate intracellular stores of GSH protect against peroxide-mediated loss of GPx-1 activity, as addition of GSH to cultures minimized enzymatic inactivation of GPx-1 by exposure to high concentrations of peroxides, whereas buthionine sulfoximine, an inhibitor of GSH biosynthesis, augmented sensitivity to peroxide-induced GPx-1 inactivation (373)

doi: 10.3389/fpubh.2020.00152

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