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MAP1643 encodes an isocitrate lyase, an essential enzyme that mediates the cleavage of isocitrate to succinate and glyoxylate, a part of glyoxylate shunt or the tricarboxylic acid cycle (TCA cycle)

Additionally, the mechanical disruption of the impact can cause damage to microtubules, leading to axonal swelling, disruption of axonal transport, and eventual disconnection (Step 9)

Nanotechnol Health Care

Retrieved 1 January 2021

In MASLD, intracellular cholesterol buildup leads to the generation of cytotoxic oxysterols that activate pro-inflammatory cascades and ER stress [11]

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