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Results: L-TMEM41B single KO mice had massive hepatic steatosis by 1 month with a decrease in VLDL secretion

Additional research supported this, showing that butyrate-mediated HDAC2 inhibition reduced hepatic fibrosis in biliary atresia [64]

doi:10.1016/s0925-4439(99)00077-0 259

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Furthermore, THC demonstrates neuroprotective potential, exemplified by its capacity to modulate the Ras/ERK signaling pathway, thereby alleviating cell cycle arrest and inhibiting apoptosis of microglia in Alzheimers disease models [2,3,4,5]

In the CNS immune system, activation of microglial cells results in the neuroinflammation responsible for the elimination of pathogens, toxic components, and dead cells