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Some samples also contained arsenic and lead at levels exceeding established safety limits for injectable drugs

Gastroenterology 150 , 13801392 (2016)

doi:10.3390/ijms27062876 Note: every reference above is a study of a single compound

Beti-cel is generated by ex vivo transduction of autologous CD34 + hematopoietic stem and progenitor cells HSPC) with the lentiviral vector BB305, which is a replication defective, self-inactivating (SIN), third-generation HIV-1 based lentiviral vector engineered to deliver a variant of the human -globin gene modified at codon 87 (T87Q) (Fig