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CD4 + CD25 + Foxp3 + Tregs cell dysfunction is common in autoimmune diseases (199), and it may be converted into pathogenic Th17 cells after repeated amplification (200)

[] Cholesterol, phospholipids, bilirubin, and GSH are transported into the bile duct through ATP-binding cassette subfamily G member 5/8 (ABCG5/8, for cholesterol), multidrug resistance protein 3 (MDR3

Exploring the Molecular Mechanisms and Therapeutic Potentials of Essential Oils: A Systems Biology Approach

10.1080/10428194.2019.1675881 112 MattarM.UmutoniF.HassanM

doi: 10.1016/j.freeradbiomed.2018.08.014

Additionally, some patients may experience paradoxical worsening or develop new chemotherapy-induced peripheral neuropathy (CIPN) after BTZ discontinuation, a phenomenon known as coasting, which can lower survival rates, particularly in children and adolescents (Tay et al., 2022