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In a recent investigation undertaken by our group, adult mice with partial IGF-1 showed a decrease in the expression of genes involved in glucose metabolism (phosphoenolpyruvate carboxylase-1, glucose-6-phosphatase, pyruvate dehydrogenase kinase isoenzyme-4, and ATP-citrate lyase), resulting serious hyperglycaemia [164]

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Each component is independently tested for purity (99%+) and potency, then combined in precise ratios for consistent, reproducible results

TB-500 is generally more expensive at equivalent doses because 17-mer fragment synthesis is technically more delicate