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Recent studies show EVs inhibit ferroptosis through multiple pathways to improve diabetic wound healing

Overall, Gpx4 plays a critical protective role in the proliferation and function of immune cells, although certain immune cell subsets may not rely heavily on Gpx4 protection, possibly due to their distinct energy metabolic activities and antioxidant mechanisms

FEBS Open Bio (2021) 11(2):45667

Cytotoxicity was determined using a 3-(4,5-dimethyl 2-thiazolyl)-2,5-diphenyl-2H-tetrazolium bromide (MTT) assay

GPx activity was determined using a colorimetric method [58]

High levels of oxidative stress may contribute to ALS onset, increasing motoneurons death, and heavy metals may be a cause for the increase of ROS