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Given the increased expression of cysteine catabolic enzymes, such as cystathionine -synthase (CBS), cystathionine -lyase (CSE) and 3-MST in different cancer cell types, it is likely that their relevance for cancer development is shared between the production of H 2 S (detailed later in the article) and the accompanying generation of metabolites that constitute carbon sources

Oxidative modification of ER-resident chaperones and Ca 2+ -handling proteins can aggravate the unfolded protein response and disturb Ca 2+ release, thereby feeding back into mitochondrial dysfunction and further ROS generation

Minocycline-induced pigmentation of the skin and nails

Neurobiol Dis 48:418428 Lobsiger CS, Boillee S, Cleveland DW (2007) Toxicity from different SOD1 mutants dysregulates the complement system and the neuronal regenerative response in ALS motor neurons

Affecting particle fate, the Vroman effect controls the adsorption and desorption dynamics of the protein corona

Fibroids are extremely heterogeneous in their pathophysiology, size, location and clinical symptomatology