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Acknowledgements We thank Nadine Bley and the Core Facility Imaging for assistance with microscopy and adhesion assays, Stefan Httelmaier for kindly providing the vector pMD2.G, psPAX2 and pLVX-shRNA2, Reinhard Hoffmann for the transcriptome data analysis, Elisabeth Bormann for technical help with Figure 7, and Pascal Rudewig and Anja Weber for excellent technical assistance.

Synthetic farnesoid X receptor agonists induce high-density lipoprotein-mediated transhepatic cholesterol efflux in mice and monkeys and prevent atherosclerosis in cholesteryl ester transfer protein transgenic low-density lipoprotein receptor (-/-) mice

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Upon binding to the cognate receptors, the peptide may trigger downstream signaling, which may mobilize the fat cells from storage mode to a usable state by enhancing the rate of metabolism

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Vaccine 24 , 10281034 (2006)