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GXL94, GXL50, SCL43 cells were resuspended and cultivated at 37C for 2 h in fresh sterilized MRS broth containing different concentrations of H 2 O 2 (0, 2, 4, 6, 8, 10, 12, 14, 16, 18, 20, and 22 mM) after adjusted OD 600 to 0.80

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In BP, notable enrichment terms were observed in phosphorylation, response to hormone, positive regulation of phosphorylation, response to xenobiotic stimulus, positive regulation of programmed cell death and others

Funding This work was supported by grants from Zhejiang Lingyan R&D Research and Development Project (2024C03165), Noncommunicable Chronic Diseases-National Science and Technology Major Project (2023ZD0507500), National Natural Science Foundation of China (82570790 and 82270704), Zhejiang provincial program for the Cultivation of High-level Innovative Health talents, Nature Science Foundation of Ningbo (2023J160), and Youth Scientist Project of Key Projects under Jiangxi Provincial R & D Program (20243BBI91026)