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Heazell AE, Lacey HA, Jones CJ, Huppertz B, Baker PN, Crocker IP

Quantitative assessments, including zonal variation in collagen fiber size and fat-collagen distance measurements, are underway

Another 68-week trial with over 3000 obese or overweight adults found 17.4% body weight loss with semaglutide versus only 2.9% with placebo plus diet/exercise counseling

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In addition to these findings, in vivo evidence of IgG1-3 pathogenicity is provided by a model in which a mouse knockout of murine IgG1-equivalent to human IgG4-developed myasthenic features when immunized against MuSK