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Together these results suggest that P-gp overexpression confers tamoxifen induced oxidative cell death of drug resistant cells

- Glutathione is a powerful antioxidant synthesized within cells from the combination of three amino acids (glutamic acid, cysteine, and glycine)

An expert analysis must weigh the encouraging proof-of-concept from preclinical models against the sobering realities of clinical translation

516(Pt 65 MiyakoshiN.KasukawaY.LinkhartT

Boughton-Smith NK, Evans SM, Hawkey CJ, Cole AT, Balsitis M, Whittle BJ, et al Nitric oxide synthase activity in ulcerative colitis and Crohn's disease Lancet