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Benzyl alcohol concentration must be exactly 0.9% 0.1% to provide bacteriostatic activity without denaturing peptide structureconcentrations below 0.5% fail to prevent microbial growth, while concentrations above 1.5% cause aggregation

MRD- rate in the intent-to-treat population was 29.6% in IKEMA and 17.6% in CANDOR at 12 months

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While we acknowledge concerns that a hospital may not have the opportunity to respond to performance results between the implementation of the star cap and the 1-star reduction, we note that the Safety of Care measure group and its component measures have been a prominent part of the Overall Hospital Quality Star Rating since its inception, with hospitals' Safety of Care performance already contributing substantially to their Overall Hospital Quality Star Rating

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Yesbacteriostatic water contains 0.9% benzyl alcohol, which inhibits bacterial growth and allows reconstituted peptides to remain sterile for up to 28 days under refrigeration