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Optimal glutathione levels help maintain healthy immune cell function.

Following mitochondrial damage, PINK1 accumulates on the OMM and phosphorylates the serine (Ser)65 residue of ubiquitin, even when present at low levels (50)

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Bisogno T, Melck D, Petrocellis L, Marzo V (2008) Phosphatidic acid as the biosynthetic precursor of the endocannabinoid 2-arachidonoylglycerol in intact mouse neuroblastoma cells stimulated with ionomycin

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This, in addition to the differences in magnitude and type of GES changes, suggest that STRIDE and D+B have distinct and potentially complementary mechanisms of action