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On the other hand, lysosomal CD63 may contribute to insulin degranulation in ob/ob diabetic mice (Pasquier et al., 2019)

Severe oxidative stress at the intestinal mucosa may lead to the loss of tight junction proteins through processes including the thiol oxidation, nitration, phosphorylation, and carbonylation of cytoskeletal proteins, tight junction proteins, and intracellular regulatory proteins 89