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Pathological outcomes are more likely to emerge when adaptive mechanisms are overwhelmed by chronic stressors, persistent chronodisruption, or underlying disease processes

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In general, such fusion proteins are soluble and can easily be purified from lysed cells by adsorption and binding to matrix glutathione-agarose beads followed by elution in the presence of free glutathione

Gunderson, F.Q., Merkhofer, E.C