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J Cardiometab Syndr

1 Iron overload profoundly affects the immune system by inhibiting the phagocytosis of macrophages and monocytes, increasing the number and viability of inhibitory T cells, limiting the proliferative ability of T helper cells, and changing the distribution of lymphocytes within the immune system

Because Ggt1 overexpression and abnormal glutamate accumulation damage cells, these excess glutathione conjugates must be cleared from the cell, followed by subsequent glutathione metabolite recycling to protect the system from toxin-induced kidney impairment and maintain the redox balance

Yu Q, Lee CF, Wang W, et al

41 LohmannW.KarstU

Ascorbic acid: The chemistry underlying its antioxidant properties