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FIGURE 4-26 Hypochromic erythrocytes in blood from a dog with iron deficiency secondary to chronic blood loss resulting from a persistent flea infestation

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Although the retro-inverso approach may fail to accurately reproduce biological function in the context of helical structures (e.g., p53 or HIV-1 proteins), certain exceptionssuch as the binding of a p53-derived retro-inverso peptide to its regulator MDM2demonstrate that well-designed D-peptides can, in specific cases, effectively mimic the function of the original peptide

and Bridge, W.J., Oral administration of -glutamylcysteine increases intracellular glutathione levels above homeostasis in a randomised human trial pilot study

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