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This solution is typically applied daily

Li DW, Wang YD, Zhou SY, Sun WP (2016) -Lipoic acid exerts neuroprotective effects on neuronal cells by upregulating the expression of PCNA via the P53 pathway in neurodegenerative conditions

The tripeptide sequence glycyl-L-histidyl-L-lysine wraps around a copper ion, creating a structure with remarkable stability when handled correctly and surprising fragility when handled wrong

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Another reported needing consistent daily application for results