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Occupational and environmental exposures to this toxic metal remain a global health problem [1]

10.1016/j.tice.2023.102036 50 SeverI.OzkulB.Erisik TanrioverD.OzkulO.ElgormusC.GurS.et al (2021)

In addition, the role of physical exercise in brain function recovery and neuronal repair should not be overlooked [47, 79]

IS provided expert opinion and contributed to the writing of the manuscript

Moreover, the release of IL-18 at 10 M doses and IL-8 at 10 M and 20 M doses were significantly increased in contrast to LVX (Fig

Results Molecular analysis reveals structural stability of GRLX and pKa of individual cysteines Given the previous observations that GLRX can be inactivated via an oxidative mechanism 8,23 , herein we sought to investigate the relative vulnerability of each of the individual cysteines towards GSSG, a model glutathionylating agent, or H 2 O 2 and their contribution to oxidative inactivation