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Due to the complicating factor of a shot and the extra cost, it seems the best route for most people is to focus on getting adequate B vitamins from food, and supplement as necessary.

If you want to take a magnesium supplement, Tang suggests limiting your dose to no more than 400 milligrams a day, which is generally considered a safe amount

Exposure to light, heat, or atmospheric oxygen degrades the copper-peptide bond within 72 hours at room temperature

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This is not guaranteed, as individual responses vary, but it is the most commonly reported benefit