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& Gonzalez-Gallego, J

Without adequate glutathione reserves, acetaldehyde accumulates in hepatocytes and crosses the blood-brain barrier, where it disrupts neurotransmitter synthesis and causes the cognitive symptoms of hangover

These are hormone signaling chemicals produced in the brain that stimulate the production and release of your own natural Human Growth Hormone from the pituitary gland and hypothalamus

however, the precise role attributed to acetate in this regard still remains to be clarified

It does so by neutralizing the metal ions in the formula (that usually get into there from water) that would otherwise cause some not so nice changes