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This involves histamine release due to a direct action of the medication (not an IgE-mediated allergic reaction)

doi: 10.1007/s40618-016-0559-9 4 MarcocciCKahalyGJKrassasGEBartalenaLPrummelMStahlMet al

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V.Prashanthi DeviM.KirubagaranR

Notably, in ferroptosis, an increase in ferritinophagy activation and a decrease in mitophagy activation were noted, despite the continuous elevation in intracellular iron content, mitochondrial quantity, and ROS [289]