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Acknowledgements This work was carried out on behalf of the Pan American League of Associations for Rheumatology (PANLAR)

However, their effect may be particularly dose-dependent and more research is needed before specific recommendations can be made

AMPK plays an important role in autophagy by regulating energy metabolism, and its major function is regulating the autophagy process [19]

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Melanoma In a study of melanoma, it was found that miR-137 negatively regulates ferroptosis by directly acting on the glutamine transporter SLC1A5 in melanoma cells, while knockdown of miR-137 promotes ferroptosis 53