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Injectable GHK-Cu is delivered systemically rather than absorbed through the skin, which produces different (and generally more pronounced) systemic effects than topical copper peptide cosmetics

KPV, also known as Lysine-proline-valine, is a naturally occurring tripeptide [that] has been shown to attenuate the inflammatory responses of colonic cells[and] exerts its anti-inflammatory function inside cells, where it inactivates inflammatory pathways (Xiao et al., 2017)

Is the delivery claim supported by formulation data

10.3389/fendo.2022.1059473 [DOI] [PMC free article] [PubMed] [Google Scholar] Bonnecaze A

Furthermore, a network comprising 8 key strains, 14 key genes and 83 key metabolites was constructed