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The tools for peptide isolation, the chromatographic methods, the analytical chemistry all of these would have to be developed before the philothion of 1888 could become the glutathione of the twentieth century

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Lead-time bias was corrected for using the parametric method proposed by Duffy et al

Importantly, we found that TGFb ligand treatment induced an up-regulation of the SNCA gene upon aSyn overexpression