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Clinical perspective on oxidative stress in sporadic amyotrophic lateral sclerosis

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Elevated homocysteine is a modifiable risk factor that can often be reduced through appropriate nutritional and lifestyle interventions

In this context, TAMs, through their privileged control of iron flux and redox signalling, can orchestrate whether ferroptotic stress becomes tumor-eradicating or merely adaptive [16]

Residual genomic DNA was removed by DNase I treatment, and RNA samples were subsequently purified with AMPure XP beads (Beckman Colter Life Sciences) and eluted in 1 TE buffer

The GCLC floxed X CaMKII-Cre mouse was named here as GCLC-KO for the sake of convenience