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Independent replication, off-target profiling, and assessment in sorafenib-resistant and normal hepatocytes are needed before translational conclusions

P2.159 Efflcacy and safety of once-daily (qd) pramipexole extended-release for advanced Parkinson's disease Parkinsonism and Related Disorders

EPAC and PKA inhibit the human airway smooth muscle induced by a cigarette smoke extract (CSE) by blocking the activation of the NF-B and ERK, respectively, and by releasing neutrophil chemokine IL-8, which together exert anti-inflammatory effects