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While hydrogen peroxide toxicity requires concentrations in the micromolar range, concentrations in the nanomolar range can promote signaling ( N -acetyl-L-cysteine (NAC) blunts glucose- or KCl-stimulated insulin secretion in INS 832/12 cells ( While no studies have observed direct evidence for the existence of redox relays in -cells, there is sufficient evidence that activity of peroxiredoxins, thioredoxin, or thioredoxin reductase promotes GSIS

doi: 10.14719/PST.2460 41 DingR.-X.GohW

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ChemBioChem 20:900905 CrossRefGoogle Scholar S -metolachlor herbicide