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In this context, recent studies have shown that in colostrum and mature milk, IL-2, IL-10, and IFN- are higher at night, while IL-6 and TNF- are higher during the day, exhibiting circadian rhythms

While tests such as CVLT, BNT, and UPSIT offer valuable diagnostic insight, particularly in early or prodromal stages, their limited dynamic range and susceptibility to ceiling or floor effects constrain their utility as response biomarkers

Given the plethora of information on the immunological pathophysiology of MS and the accessibility of existing drugs as well as novel ones in development, the future seems promising for managing and treating MS

Journal of the American College of Nutrition, 22 , 1835

Chronic treatment of RT has been long used in the effective induction of PD both in Rat 44,45,46 and zebrafish models 47,48,49

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