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The kidneys and nervous system are similarly sensitive to biochemical imbalances over time

However, outcomes remained consistently above baseline through 12 months, and mean improvements at later follow-up continued to meet commonly used thresholds for clinical importance

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Organic acids testing (hippuric acid, pyroglutamic acid, methylation markers) provides indirect evidence of amino acid conjugation and glutathione status

No physiological or quantitative changes were detected in the OLZ-injected group

[DOI] [PMC free article] [PubMed] [Google Scholar] Sauve AA, Wolberger C, Schramm VL, Boeke JD