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Bioorg Med Chem 2001, 9: 13711384

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Among the seven inhibitors used, only DFO and ferrostatin 1 were able to significantly prevent cell death, whereas CA074 only partially reduced cell death induced by TMZ, alone or in association with QN, in both cell lines (Fig

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Glutathione is a tripeptide (composed of 3 amino acids), the central one a cysteine which can be in a reduced (GSH) or oxidized form where it forms a dimer with a cysteine from another glutathione molecule (denoted GSSG)