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This approach significantly accelerates the downscaling process compared to traditional numerical dynamical models, making it highly suitable for a broad range of important applications, such as downscaling seasonal forecasts or climate projections

b , Depth dependence of two-photon-excited HyPerFLEX signal in brain tissue using HBR-3,5-DOM (orange triangles) and N871b (red circles) fluorogens plotted against tissue depth

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