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Biochem Biophys Res Commun (2020) 522(2):41521

Takeuchi M, Yamagishi S

If it spreads, becomes painful, or you develop systemic signs, seek medical evaluation without delay

However, it is not a standalone diagnostic test but is often used together with other liver tests to provide a more accurate diagnosis

British national formulary

It should also be noted that HIV infection is associated with an increased risk of pituitary gland stroke as well as pituitary lymphoma and may therefore lead to hypopituitarism, one of the effects of which is infertility (71)